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Extracerebral decarboxylase inhibitor : ウィキペディア英語版 | Extracerebral decarboxylase inhibitor
Extracerebral decarboxylase inhibitor is an inhibitory enzyme. It is used to inhibit the decarboxylation of L-DOPA to Dopamine outside the brain, i.e. in the blood. This is primarily co-administered with L-DOPA to combat Parkinsons Disease. Administration can prevent common side-effects, such as nausea and vomiting, as a result of interaction with D2 receptors in the vomiting center (or cheomoreceptor trigger zone) located outside the blood–brain barrier. Examples of extracerebral decarboxylase inhibitors include Carbidopa and Benserazide. ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Extracerebral decarboxylase inhibitor」の詳細全文を読む
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